Research Publications

Click here for a list of publications in PubMed

Recent Publications:

Enders JD, Thomas S, Lynch P, Jack J, Ryals JM, Puchalska P, Crawford P, and Wright DE. (2023) ATP-Gated Potassium Channels Contribute to Ketogenic Diet-Mediated Analgesia in Mice. Neurobiology of Pain. PMCID: PMC10245818.

Enders J, Jack J, Thomas S, Lynch P, Lasnier L, Cao X, Swanson MT, Ryals J, Thyfault J, Puchalska P, Crawford PA, Wright DE. (2023) Ketolysis is Required for Proper Development and Function of the Peripheral Nervous System. Experimental Neurology. PMID: 37100111.

Thomas SJ, Enders J, Rovenstine L, Kaiser A, Heslop L, Hauser W, Chadwick A, and Wright DE.  (2023) Intraepidermal Nerve Fiber Density in Disease. Frontiers in Neuroscience. PMID: 36798392.

Enders J, Elliott D, Wright DE. (2022) Emerging Nonpharmacologic Interventions to Treat Diabetic Peripheral Neuropathy. Antioxid Redox Signal. PMID: 36503268.

Enders JD, Thomas S, Swanson MT, Ryals JM, Wright DE. (2022) A ketogenic diet prevents methylglyoxal-evoked nociception by scavenging methylglyoxal. Pain. PMID: 35500286.

Enders J, Swanson, T, Ryals, JM, Wright DE (2021) A ketogenic diet reduces mechanical allodynia and improves epidermal innervation in diabetic mice. Pain. PubMed PMID: 34252910

Wu PY, Menta B, Visk, A, Ryals, JM, Christianson JA, Wright, DE, Nicol, AN (2021) The impact of foot shock-induced stress on pain-related behavior associated with burn injury. Burns. PubMed PMID: 33958242.

Fuentes IM, Jones BM, Brake AD, Pierce AN, Eller OC, Supple RM, Wright DE, Christianson JA. (2020) Voluntary wheel running improves outcomes in an early life stress-induced model of urologic chronic pelvic pain syndrome in male mice. Pain. PubMed PMID: 33399417.

Wu PY, Yang X, Wright DE, Christianson JA. (2020) Stress-induced bladder hypersensitivity, hind paw allodynia, and depression-like behavior in an anxiety-prone strain of mice. Pain;161(1):211–219. PubMed PMID: 31568043.

Feldman EL, Callaghan BC, Pop-Busui R, Zochodne D, Wright DE, Bennett D, Bril V, Russell J, Viswanathan V. (2019) Nature Reviews Disease Primer: Diabetic Neuropathy. Nature Reviews Disease Primers. Jun 13;5(1):41. Review. PubMed PMID: 31197153.

Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE. (2018) Reduced mitochondrial ROS production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol. 2018 Aug 8. doi: 10.1113/EP087083. PubMed PMID: 30088302.

Cooper MA, O'Meara B, Jack MM, Elliot D, Lamb B, Khan ZW, Menta BW, Ryals JM Winter MK, Wright DE. (2018) Intrinsic activity of C57BL/6 substrains associates with high-fat diet-induced mechanical sensitivity in mice. J Pain. pii: S1526-5900(18)30193-7. doi: 10.1016/j.jpain.05.005. PubMed PMID: 29803670.

Cooper MA, Menta BW, Sanchez Perez C, Jack MM, Khan ZW, Hayley PM, Ryals JM, Winter M, Wright DE. (2018) A ketogenic diet reduces metabolic syndrome-induced allodynia and promotes peripheral nerve growth in mice. Exp Neurol. May 17;306:149-157. PubMed PMID: 29763602.

Grote CW, Wilson NM, Katz NK, Guilford BL, Ryals JM, Novikova L, Stehno-Bittel L, Wright DE. (2018) Deletion of the insulin receptor in sensory neurons increases pancreatic insulin levels. Exp Neurol. pii: S0014-4886(18)30086-4. doi:10.1016/j.expneurol. 04.002. PubMed PMID:29649429.

Cooper MA, Jack MM, Ryals JM, Hayley P, Escher T, Koch LG, Britton SL, Raupp, SM, Winter MK, McCarson KE, Geiger PC, Thyfault JP, Wright DE. (2017) Rats bred for low and high running capacity display alterations in peripheral tissues and nerves relevant to neuropathy and pain. Brain Behav. 2017 Sep 6;7(10):e00780. doi:10.1002/brb3.780. PubMed Central PMCID: PMC5651381.

Guilford BL, Parson JC, Grote CW, Vick SN, Ryals JM, Wright DE. (2017) Increased FNDC5 is associated with insulin resistance in high fat-fed mice. Physiol Rep. 5(13). pii: e13319. PubMed PMCID: PMC5506519.

Guilford BL, Ryals JM, Selfridge JE, E L, Swerdlow RH, Wright DE. (2017) Dorsal root ganglia mitochondrial function in nondiabetic and streptozotocin-induced diabetic mice fed a standard or high-fat diet. J Neurol Neurosci. 8(2) pii: 180. PubMed PMCID PMC5538136.

Abuzinadah AR, Kluding PM, Wright DE, D’Silva, L Ryals J, Hendry B, Jawdat O, Herbelin L, McVey A, Barohn RJ, Dimachkie M, Pasnoor M. (2017) Less is more in diabetic neuropathy diagnosis: comparison of quantitative sudomotor axon reflex and skin biopsy. J. Clinical Neuromuscular Diseases. 2017 19(1):5-11. PubMed PMID:28827483.

Grote, CW, Wright DE. (2016) A role for insulin in diabetic neuropathy. Review. Frontiers in Neuroscience. 10:581. PubMed PMCID: PMC5179551.

Cooper MA, Ryals JM, Wu PY, Wright KD, Walter KR, Wright DE. (2016) Modulation of diet-induced mechanical allodynia by metabolic parameters and inflammation. J Peripher Nerv Syst. Dec 9. doi: 10.1111/jns.12199. PubMed PMID: 27935216.

Cooper, M, Kluding PM, Wright DE. (2016) Exercise as an intervention for inflammation-driven diabetic neuropathy. Review. Frontiers in Neuroscience.10:372. PMCID:PMC4993768.

Kluding PM, Pasnoor M, Singh R, D’Silva L, Yoo M, Billinger S, LeMaster J, Dimachkie M, Herbelin L, Wright DE. (2015) Safety of aerobic exercise in people with diabetic peripheral neuropathy: single-group clinical trial. Physical Therapy Journal. 95(2):223-34 PubMed PMCID: PMC4757647.